CatalogNo.: F-H090 MW: 694.04 Description: Zn(II)DeuteroporphyrinIX2,4bisethyleneglycolisaninhibitorofhemeoxygenase(theenzymethatcatalyzestheconversionofhemetobiliverdininthehemedegradationpathway)atconcentrationsaslowat0.5μM.Hemeoxygenasehasbeenimplicatedintumorcellresistancetochemotherapy,reductionoffreerADIcalformationandinflammation,andassociatedwithvascularrepair. | |||
StorageZn(II)DeuteroporphyrinIX2,4bisethyleneglycolisstableforatleastoneyearwhenstoredasasolid,protectedfrommoisture,at-20°C.Protectfromlight.References1)Chernick,R.J.,P.Martasek,etal.(1989)."Sensitivityofhumantissuehemeoxygenasetoanewsyntheticmetalloporphyrin."Hepatology10(3):365-9.2)Jozkowicz,A.,H.Was,etal.(2007)."Hemeoxygenase-1intumors:isitafalsefriend?"AntioxidRedoxSignal9(12):2099-117. 3)Abraham,N.G.andA.Kappas(2005)."Hemeoxygenaseandthecardiovascular-renalsystem."FreeRadicBiolMed39(1):1-25. 4)Kim,D.H.,A.P.Burgess,etal.(2008)."Hemeoxygenase-mediatedincreasesinadiponectindecreasefatcontentandinflammatorycytokinestumornecrosisfactor-alphaandinterleukin-6inZuckerratsandreduceAdipogenesisinhumanmesenchymalstemcells."JPharmacolExpTher325(3):833-40. |
产品名 | 货号 | 公司分类 | 分类 | 美金价 |
Viskase/透析袋 MD25(3500)/25mm/MD25-3.5 | MD25-3.5 | 透析 | 透析 | 1543.14 | 指尖陀螺 | 1221 | 常用设备 | 4.50 |