CatalogNo.: E-8000 Description: HumanINPP4AwithN-terminal6-HistagwasexpressedinSf9cellsandpurifiedusingmetalchelatingchromatography. | |||
INPP4Aisamagnesium-independentphosphataseinvolvedinthephosphatidylinositol3-kinase(PI3K)pathway.INPP4AanditsisoenzymeINPP4Bhydrolyzethe4phosphatefromthelipidsecondmessengerphosphatidylinositol-3,4-bisphosphate(PI(3,4)P2)toformphosphatidylinositol-3-phosphate(PI(3)P).Whilelittleevidencesupportsitsroleasatumorsuppressor,INPP4AdoessuppressglutamateexcitotoxicityinthecentralnervoussystemandisresponsIBLefortheWeeblemousephenotype.AspontaneousframeshiftmutationintheInpp4ageneispresentintheWeeblemouseresultinginselectiveneuronallossinthecerebellumresulting,severeataxiaandearlydeath. Storage-70°CorbelowRelatedProductsINPP4AcitvityELISA(K-5200)INPP4substrates:diC8-PI(3,4)P2(P-3408),diC16-PI(3,4)P2(P-3416) MalachiteGreenPhosphataseAssayKits |
产品名 | 货号 | 公司分类 | 分类 | 美金价 |
Viskase/透析袋 MD25(3500)/25mm/MD25-3.5 | MD25-3.5 | 透析 | 透析 | 1543.14 | 指尖陀螺 | 1221 | 常用设备 | 4.50 |