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实验室透析袋
℡ 4000-520-616
℡ 4000-520-616
echelon-inc/PI4-Kinase beta (PI4Kb), active/10ug/P32-10G-10ug
产品编号:P32-10G-10ug
市  场 价:¥5900.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$295.00
品      牌: Echelon
公      司:VISKASE
公司分类:
echelon-inc/PI4-Kinase beta (PI4Kb), active/10ug/P32-10G-10ug
商品介绍

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CatalogNo.: P32-10G

Description: Description:Full-lengthrecombinanthumanPI4KBwasco-expressedbybaculovirusinSf9insectcellsusinganN-terminalGSTtag.EnzymeobtainedfromSignalchem.


Molecularweight:~120kDa

Sequence:Fulllength

Species:Human

Tag:GSTtag

Purity:>90%(seeTDSforlotspecificinformation)

SpecificActivity:>30nmol/min/mg(seeTDSforlotspecificinformation)

ExpressionSystem:Sf9insectcellsusingbaculovirus

GeNEBankNumber:BC000029

Applications:PI4-Kinaseassay,westernblot.



Formulation:Recombinantproteinstoredin50mMTris-HCl,pH7.5,150mMNaCl,10mMglutathione,0.1mMEDTA,0.25mMDTT,0.1mMPMSF,25%glycerol.

StorageandstABIlity:Storeproductat-70ºC.Stableuptooneyear.


ScientificBackground:PI4KBisamemberofthephosphatidylinositol4-kinasefamily(PI4K)andisthefirstcommittedstepintheproductionofthesecondmessengerinositol-1,4,5-trisphosphate(PIP3).PI4KBregulatesthegolgidisintegration/reorganizationduringmitosispossIBLyviathephosphorylationofphosphatidylinositol.PI4KBisatypeIIIenzymethatissensitivetowortmanninandisresponsibleforregulatingthesynthesisofagoNIST-sensitivepoolsofpolyphosphoinositides.PI4KBiscriticalforglucose-inducedinsulinsecretionduetoitscapacitytoregulatethereleaseofsecretorygranules.PI4KBinhibitstheinsulin-stimulatedtranslocationofglucosetransporter-4inmouseADIpocytesthroughitsinteractionwithneuronalcalciumsensor-1.



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PI4KIIIb(P-22-10G)

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