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实验室透析袋
℡ 4000-520-616
℡ 4000-520-616
echelon-inc/Akt3, active/20ug/E-K003-20ug
产品编号:E-K003-20ug
市  场 价:¥11580.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$579.00
品      牌: Echelon
公      司:VISKASE
公司分类:
echelon-inc/Akt3, active/20ug/E-K003-20ug
商品介绍

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CatalogNo.: E-K003

Description: Recombinantfull-lengthhumanAkt3containingN-terminalGSTtagwasexpressedbybaculovirusinSf9insectcells.
ThegeneaccessionnumberisNM_005465.
Thismaterialissoldforresearchpurposesonly.
SpecificActivity
206nmolphosphateincorporatedintoAktsubstratepeptideperminutepermgproteinat30°Cfor15minutesusingafinalconcentrationof50µMATPandtotalof0.83µCi/µlP-32.

ScientificBackground

  • Akt3orProteinKinaseBã(PKBã)isaserine/threoninekinasethatisamemberoftheAktfamily.Inmammals,theAktfamilycomprisesofthreehighlyhomologousmembersknownasAkt1(PKB),Akt2(PKB),andAkt3(PKB).Akt3liketheotherfamilymembersisactivatedincellsexposedtodiversestimulisuchashormones,growthfactors,andextracellularmatrixcomponents.Theactivationmechanismremainstobefullycharacterizedbutoccursdownstreamofphosphoinositide3-kinase(PI3K).PI3Kgeneratesphosphatidylinositol-3,4,5-trisphosphate(PIP3),alipidsecondmessengeressentialforthetranslocationofAktfamilymemberstotheplasmamembranewheretheyarephosphorylatedandactivatedbyphosphoinositide-dependentkinase-1(PDK-1)andphosphoinositide-dependentkinase-2(PDK-2possIBLyILK).Akt3liketheotherfamilymembersphosphorylatesandregulatesthefunctionofmanycellularproteinsinvolvedinprocessesthatincludecellularmetabolism,survival/apoptosis,andproliferation.Rec

    Storage

    • Storeproductfrozenatorbelow-70°C.Stablefor1yearat-70°Casundilutedstock.Aliquottoavoidrepeatedthawingandfreezing.
    品牌介绍
    产品名货号公司分类分类美金价
    Viskase/透析袋 MD25(3500)/25mm/MD25-3.5MD25-3.5透析透析1543.14
    指尖陀螺1221常用设备4.50
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    CIF100%正规报关,提供发票
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