ScientificBackground- Srcfamilybelongstonon-receptortyrosinekinases.SrcwasoriginallyidentifiedasatransformingproteinoftheRoussarcomavirus(RSV)thathadenzymaticABIlitytophosphorylatetyrosineinproteinsubstrates.Srcisoverexpressedandactivatedinalargenumberofhumanmalignanciesandhasbeenlinkedtothedevelopmentofcancerandprogressiontodistantmetastases.Inadditiontoincreasingcellproliferation,akeyroleofSrcincancerseemstobetheabilitytopromoteinvasionandmotility,functionsthatmightcontributetotumourprogression.OncogenicformsoftheSrcaltercellstructure,inparticulartheactinCytoskeletonandtheadhesionnetworksthatcontrolcellmigration,andalsotransmitsignalsthatregulateproliferationandcellsurvival.RecentworkindicatesthatSrcplaysaroleinthesefunctionsbyinfluencingtheRhoA-ROCKpathwaythatcontrolscontractileactinfilamentassembly,theSTATfamilyoftranscriptionfactorsneededfortransformation,andtheCblubiquiti
Storage- Storeproductfrozenatorbelow-70°C.Stablefor1yearat-70°Casundilutedstock.Aliquottoavoidrepeatedthawingandfreezing.
产品名 | 货号 | 公司分类 | 分类 | 美金价 | Viskase/透析袋 MD25(3500)/25mm/MD25-3.5 | MD25-3.5 | 透析 | 透析 | 1543.14 | 指尖陀螺 | 1221 | | 常用设备 | 4.50 |
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