CatalogNo.: L-9318 MW: 466.61 CAS: 645408-60-2 Description: OMPTisametabolically-stABIlizedanalogofLysophosphatidicAcid(LPA)whichactsaspotentagoNISTfortheLPA3receptor.Ofthetwoenantiomers,(2S)-OMPTismorepotentthan(2R)-OMPTshowing5-20foldmoreactivityincalciumreleasefromLPA3-transfectedSf9andrathepatomaRh7777cells.(2S)-OMPTisalsomorepotentininducingcalciumrelease,IL-6production,andMAPKandAktphosporylationinOVCAR3cells. | |||
Storage-20°CFeaturedinPublications1)Qian,L.,Y.Xu,etal.(2003)."EnantioselectiveresponsestoaphosphorothioateanalogueoflysophosphatidicacidwithLPA3receptor-selectiveagonistactivity."JMedChem46(26):5575-8.2)Altman,M.K.,V.Gopal,etal.(2010)."Targetingmelanomagrowthandviabilityrevealsdualisticfunctionalityofthephosphonothionateanalogueofcarbacyclicphosphatidicacid."MolCancer9:140. |
产品名 | 货号 | 公司分类 | 分类 | 美金价 |
Viskase/透析袋 MD25(3500)/25mm/MD25-3.5 | MD25-3.5 | 透析 | 透析 | 1543.14 | 指尖陀螺 | 1221 | 常用设备 | 4.50 |